Origin and Habitat: Tlayacapan, Morelos (Mexico, Northern America)
Altitude range: 1150-1800 metres above sea level.
Habitat and ecology: Mammillaria crassiorSN|13809]]SN|13809]] grows together with Agave horridaSN|1680]], Agave horridaSN|1680]], Hechtia sp. and Selaginella sp.

• Mammillaria crassior Repp.

• Mammillaria spinosissima Lem.
• Cactus spinosissimus (Lem.) Kuntze
• Neomammillaria spinosissima (Lem.) Britton & Rose
• Mammillaria centraliplumosa Fittkau
• Mammillaria centraliplumosa var. gracilis Repp.
• Mammillaria gasterantha Repp.
• Mammillaria haasii J.Meyran
• Mammillaria hermannii var. flavicans Salm-Dyck
• Mammillaria pitcayensis Bravo
• Mammillaria pretiosa var. cristata Hildm. ex C.F.Först.
• Mammillaria spinosissima var. auricoma f. cristata hort.
• Mammillaria spinosissima var. aurorea (Ehrenb.) Gürke
• Cactus auroreus Kuntze
• Mammillaria aurorea Ehrenb.
• Mammillaria spinosissima brunnea Salm-Dyck
• Mammillaria spinosissima f. brunnea (Salm-Dyck) Gürke
• Mammillaria spinosissima var. castaneoides (Lem.) Borg in Borg
• Mammillaria castaneoides Lem.
• Mammillaria spinosissima f. cristata
• Mammillaria spinosissima var. eximia (Ehrenb.) Gürke
• Cactus eximius (Ehrenb.) Kuntze
• Mammillaria eximia Ehrenb.
• Mammillaria spinosissima f. eximia (Ehrenb.) Schelle
• Mammillaria spinosissima var. flavida Salm-Dyck
• Mammillaria spinosissima f. flavida (Salm-Dyck) Gürke
• Mammillaria spinosissima var. genuina Gürke
• Mammillaria spinosissima var. haseloffii (Ehrenb.) Gürke
• Mammillaria haseloffii Ehrenb.
• Mammillaria spinosissima var. hepatica (Ehrenb.) Labour.
• Mammillaria hepatica Ehrenb.
• Mammillaria seegeri var. gracilispina Salm-Dyck
• Mammillaria spinosissima var. herrmannii (Ehrenb.) Gürke
• Mammillaria herrmannii Ehrenb.
• Mammillaria spinosissima var. isabellina (Ehrenb.) Gürke
• Cactus isabellinus (Ehrenb.) Kuntze
• Mammillaria isabellina Ehrenb.
• Mammillaria spinosissima f. isabellina (Ehrenb.) Schelle
• Mammillaria spinosissima var. linkeana (Ehrenb.) Gürke
• Cactus linkeanus Kuntze
• Mammillaria linkeana Ehrenb.
• Mammillaria spinosissima var. mirabilis (Ehrenb.) Gürke
• Cactus mirabilis Kuntze
• Mammillaria mirabilis Ehrenb.
• Mammillaria seegeri var. mirabilis (Ehrenb.) Labour.
• Mammillaria spinosissima f. monstruosa hort.
• Mammillaria spinosissima var. polyacantha (Ehrenb.)
• Mammillaria polyacantha Ehrenb.
• Mammillaria spinosissima var. pretiosa (Ehrenb.) Scheele
• Cactus pretiosus (Ehrenb.) Kuntze
• Mammillaria pretiosa Ehrenb.
• Mammillaria spinosissima var. pruinosa (Ehrenb.) Gürke
• Mammillaria pruinosa Ehrenb.
• Mammillaria seegeri var. pruinosa (Ehrenb.) Salm-Dyck
• Mammillaria spinosissima var. pulcherrima (Ehrenb.) Gürke
• Cactus pulcherrimus (Ehrenb.) Kuntze
• Mammillaria pulcherrima Ehrenb.
• Mammillaria spinosissima f. rubens (Salm-Dyck) Gürke
• Mammillaria spinosissima rubens Salm-Dyck
• Mammillaria spinosissima f. rubrispina cristata hort.
• Mammillaria spinosissima f. rubrispina hort.
• Mammillaria spinosissima var. sanguinea (F.Haage) F.Haage in L.H.Bailey ex Brandegee
• Mammillaria sanguinea F.Haage ex Regel
• Mammillaria spinosissima var. seegeri (Ehrenb.) Gürke
• Mammillaria seegerii Ehrenb.
• Mammillaria spinosissima f. tepoztlanensis Bravo
• Mammillaria spinosissima f. typica Gürke
• Mammillaria spinosissima var. vulpina (Ehrenb.) Gürke
• Cactus vulpinus var. Kuntze (Ehrenb.) Kuntze
• Mammillaria vulpina var. Ehrenb. Ehrenb.
• Mammillaria virginis Fittkau & Kladiwa in Krainz

• Mammillaria spinosissima subs. pilcayensis (Bravo) D.R.Hunt
• Mammillaria pilcayensis Bravo
• Mammillaria pilcayensis var. chrysodactyla Appenz.
• Mammillaria chrysodactyla Appenz.

• Mammillaria spinosissima subs. tepoxtlana D.R.Hunt
• Mammillaria crassior Repp.
• Mammillaria spinosissima var. auricoma (A.Dietr.) Gürke
• Cactus auricomus (A.Dietr.) Kuntze
• Mammillaria auricoma A.Dietr.
• Mammillaria spinosissima f. auricoma (A.Dietr.) Schelle

• Mammillaria spinosissima cv. Un Pico
• Mammillaria spinosissima cv. Un Pico cristata
• Mammillaria spinosissima cv. Un Pico Monstruosa

Description: Mammillaria spinosissimaSN|13809]]SN|13783]] subsp. tepoxtlana is still known by the commercial growers as Mammillaria crassiorSN|13785]]SN|13809]], but most authors have dismissed Mammillaria crassiorSN|13809]]SN|13809]] as perhaps not worthy of even varietal status, suggesting that there is not really a fundamental difference between the two and this description can be applied to all the synonyms of subsp. tepoxtlana ( see also: Mammillaria auricomaSN|13809]]SN|13785]]).
Habit: Mammillaria crassiorSN|13783]]SN|13809]] is distinguished by cylindrical stems, covered by very fine white yellow spines and lacks bristles in the axils.

Cultivation and Propagation: Mammillaria crassiorSN|13809]]SN|13809]] is an easy to grow species, just as a classic cactus, don't requires any special treatment, but need as much light as possible without burning the plant to encourage the heaviest spine formation. It is a great starter plant for the cactus grower, that readily builds up into a cluster of stems highlighted by reddish spines, further decorated by rings of purple-pink blooms.
Growth rate: It is a rapidly growing species. It offset from the base and can fill a 25 cm pot in just a few years given the best conditions.
Soils: It likes very porous standard cactus mix soil with little organic matter (peat, humus).
Repotting: Repotting every 2-3 years. As it is prone to rot under-pot in a smaller container filled with very porous compost. Use pot with good drainage.
Watering: Water regularly in summer, but do not overwater (very wet-sensitively, especially in light of its succulent root system). Its roots are easily lost in pots that stay damp for any length of time. Keep dry with ample airflow in winter. In the rest period no high atmospheric humidity!! Care must be taken with watering as they tends to become swollen and untidy in growth habit if given too much water and shade.
Fertilization: During the growing season enrich the soil using a fertilizer rich in potassium and phosphorous, but poor in nitrogen, because this chemical element doesn’t help the development of succulent plants, making them too soft and full of water.
Hardiness: It is quite frost resistant if kept dry, hardy as low as -5° C (some reports give it hardy to -12°C). However some warmth throughout the year will increase the grower's success (minimum 5° to 8°C during rest season).
Exposition: Outside bright sun, filtered sunlight or afternoon shade, inside it needs bright light, and some direct sun. Subject to sunburn if exposed to direct sun for too long. Tends to bronze in strong light, which encourages flowering and heavy wool and spine production.
Uses: It is an excellent plant for container growing. It always looks good and stays small. It look fine in a cold greenhouse and frame.
Propagation: Direct sow after last frost or (usually) or division . Seeds germinate in 7-14 days at 21-27° C in spring, remove the glass cover gradually as the plants develops and keep ventilated, no full sun for young plants! The seedlings should not be disturbed until they are well rooted, after which they can be planted separately in small pots. Cuttings: wait until the offsets that appear at the base of old clustered specimens are 1/3 the size of the parent and then detach and plant. Cuttings will take root in a minimum temperature of 20° C (but better in hot weather). Cuttings of healthy shoots can be taken in the spring and summer. Cut the stem with a sharp, sterile knife, leave the cutting in a warm, dry place for a week or weeks (depending on how thick the cutting is) until a callus forms over the wound. Once the callus forms, the cutting may be inserted in a container filled with firmed cactus potting mix topped with a surface layer of coarse grit. They should be placed in the coarse grit only; this prevents the cut end from becoming too wet and allows the roots to penetrate the rich compost underneath. The cuttings should root in 2 to 6 weeks.